2004-05-20
... ? Science & Technology at Scientific American.com: Decoding Schizophrenia -- [ NEURAL PHARMACOLOGY ] -- A fuller understanding of signaling in the brain of people with this disorder offers new hope for improved therapyThe ability of PCP and ketamine to induce a broad spectrum of schizophrenialike symptoms suggests that these drugs replicate some key molecular disturbance in the brain of schizophrenic patients. At the molecular level the drugs impair the functioning of the brain signaling systems that rely on glutamate, the main excitatory neurotransmitter in the brain.
