2003-06-26

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Guardian Unlimited | Special reports | Allergy reaction to food and surroundings affects 1 in 3 - and the NHS just can't cope

Prof Holgate said genes were partly responsible for the soaring allergy rate. "Genetics are important - allergies run in families," he said. But "the early-life experiences associated with western civilised society" must also bear some blame. "Most pronounced is the lack of exposure to agents that stimulate the immune system in early life," he said. The immune systems of babies and small children were no longer challenged by infections, dirt and bacteria because of our sterile homes and tendency to run to the doctor. Antibiotics were frequently given, even for coughs and colds which were probably viral, and wiped out the bacteria in the gut.